What it is
Clusters are grouped into major lineages (myeloid, lymphoid, epithelial, stromal, endothelial, and related groups) for rapid high-level orientation before diving into subtypes.
How to read it
Use this for first-pass triage. Lineage groups reflect broad biology before subtype resolution. Confidence indicators show certainty at the lineage level.
When to act
Clusters misassigned to an unexpected lineage may indicate doublets, ambient RNA contamination, or marker gene quality issues.
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