Resources

A curated index of articles, updates, events, and published work across single-cell research.

Insights from single-cell omics: cellular heterogeneity as a foundation of clinical outcome in chronic myeloid leukemia

Insights from single-cell omics: cellular heterogeneity as a foundation of clinical outcome in chronic myeloid leukemia

Ram Krishna Thakur, Göran Karlsson explore how single-cell omics reveals cellular heterogeneity driving clinical outcomes in CML.

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Transcriptional Roadmap of the Human Airway Epithelium Identifying HLF as a Novel Regulator of Basal Stem Cell Function

Transcriptional Roadmap of the Human Airway Epithelium Identifying HLF as a Novel Regulator of Basal Stem Cell Function

Pavan Prabhala et al. map the transcriptional landscape of human airway epithelium, identifying HLF as a key regulator.

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Alphavirus replicon particle expressing IL-12 reprograms tumor-associated macrophages and neutrophils and induces anti-tumor immunity

Alphavirus replicon particle expressing IL-12 reprograms tumor-associated macrophages and neutrophils and induces anti-tumor immunity

Momoko Ishikawa et al. show IL-12-expressing alphavirus particles reprogram tumor immune cells to induce anti-tumor responses.

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Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics

Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics

Gautam Ahuja et al. demonstrate how multi-agent AI systems enable evidence-based cell annotation in scRNA-seq data.

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Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis

Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis

Sara Palo et al. reveal how chromatin accessibility patterns shape lineage plasticity during blood cell development.

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CTEC: a cross-tabulation ensemble clustering approach for single-cell RNA sequencing data analysis

CTEC: a cross-tabulation ensemble clustering approach for single-cell RNA sequencing data analysis

Liang Wang et al. present CTEC, an ensemble clustering method for robust scRNA-seq data analysis.

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Tracking early mammalian organogenesis – prediction and validation of differentiation trajectories at whole organism scale

Tracking early mammalian organogenesis – prediction and validation of differentiation trajectories at whole organism scale

Ivan Imaz-Rosshandler et al. predict and validate cell differentiation trajectories during early mammalian organogenesis.

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Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

Rebecca Warfvinge et al. link single-cell multi-omics heterogeneity in CML to variations in therapy response.

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Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia

Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia

Daniel Zucha et al. map glial cell responses over time in a mouse brain ischemia model using spatial transcriptomics.

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Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

Radek Sindelka et al. characterize cells that initiate regeneration during Xenopus tail regrowth.

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EpiCarousel: memory- and time-efficient identification of metacells for atlas-level single-cell chromatin accessibility data

EpiCarousel: memory- and time-efficient identification of metacells for atlas-level single-cell chromatin accessibility data

Sijie Li et al. introduce EpiCarousel for efficient metacell identification in large-scale chromatin accessibility datasets.

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A guide to single-cell RNA sequencing analysis using web-based tools for non-bioinformatician

A guide to single-cell RNA sequencing analysis using web-based tools for non-bioinformatician

Sagnik Yarlagadda and Todd D. Giorgio provide a practical guide to scRNA-seq analysis using web-based platforms.

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Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

Mikael N. E. Sommarin et al. define developmental-specific populations in human fetal blood formation using multi-omics.

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Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data

Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data

Parashar Dhapola et al. introduce Scarf for memory-efficient single-cell sequencing analysis, published in Nature Communications.

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