AGI is Far, but ASI is Here
Explore how ASI transforms drug discovery by harnessing domain-specific models and advanced computing tools for faster, smarter biomedical innovation.
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A curated index of articles, updates, events, and published work across single-cell research.
A Practical Guide to Single-Cell RNA-Seq Cluster Annotation
A practical guide to scRNA-seq cluster annotation in 2026, covering marker gene inspection, reference atlas mapping, supervised classification tools, and strategies for resolving ambiguous or disease-associated populations.
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Powerful scRNA-seq Data Analysis Tools in 2025
Uncover the top single-cell RNA sequencing (scRNA-seq) and multi-omics data analytics tools of 2025. This comprehensive guide reviews 8 platforms to facilitate data analysis and reveal cellular insights.
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Transcriptional Roadmap of the Human Airway Epithelium Identifying HLF as a Novel Regulator of Basal Stem Cell Function
Pavan Prabhala et al. map the transcriptional landscape of human airway epithelium, identifying HLF as a key regulator.
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Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis
Sara Palo et al. reveal how chromatin accessibility patterns shape lineage plasticity during blood cell development.
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Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics
Gautam Ahuja et al. demonstrate how multi-agent AI systems enable evidence-based cell annotation in scRNA-seq data.
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Alphavirus replicon particle expressing IL-12 reprograms tumor-associated macrophages and neutrophils and induces anti-tumor immunity
Momoko Ishikawa et al. show IL-12-expressing alphavirus particles reprogram tumor immune cells to induce anti-tumor responses.
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Building Cell Atlases - Navigating Biology Like Google Maps Navigates the World
Discover how building cell atlases parallels Google Maps - transforming scattered cellular data into integrated, navigable maps for drug discovery.
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Understanding Batch Effect and Normalization in scRNA-Seq Data
A practical guide to batch effect correction and normalization in scRNA-seq data, covering when integration is justified, leading tools including Harmony, Seurat, BBKNN, and scVI, evaluation strategies, and how to avoid overcorrection.
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What is Single Cell Transcriptomics?
Discover single-cell transcriptomics, a transformative technique for analyzing gene expression at the cellular level in biology and medicine.
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Navigating the Complexity of Single-Cell RNA-Seq Data Analysis
Explore key challenges and advanced strategies in scRNA-seq data analysis for both new and experienced researchers.
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Overcoming Bioinformatics Skill Gaps in Single-Cell Research
Discover solutions to bridge bioinformatics skill gaps in single-cell research, enabling easier scRNA-seq analysis for wet-lab scientists.
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EpiCarousel: memory- and time-efficient identification of metacells for atlas-level single-cell chromatin accessibility data
Sijie Li et al. introduce EpiCarousel for efficient metacell identification in large-scale chromatin accessibility datasets.
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Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia
Daniel Zucha et al. map glial cell responses over time in a mouse brain ischemia model using spatial transcriptomics.
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Characterization of regeneration initiating cells during Xenopus laevis tail regeneration
Radek Sindelka et al. characterize cells that initiate regeneration during Xenopus tail regrowth.
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