Resources

A curated index of articles, updates, events, and published work across single-cell research.

Showing 46–60 of 63

Alphavirus replicon particle expressing IL-12 reprograms tumor-associated macrophages and neutrophils and induces anti-tumor immunity
Publication

Alphavirus replicon particle expressing IL-12 reprograms tumor-associated macrophages and neutrophils and induces anti-tumor immunity

Momoko Ishikawa et al. show IL-12-expressing alphavirus particles reprogram tumor immune cells to induce anti-tumor responses.

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Transcriptional Roadmap of the Human Airway Epithelium Identifying HLF as a Novel Regulator of Basal Stem Cell Function
Publication

Transcriptional Roadmap of the Human Airway Epithelium Identifying HLF as a Novel Regulator of Basal Stem Cell Function

Pavan Prabhala et al. map the transcriptional landscape of human airway epithelium, identifying HLF as a key regulator.

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Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics
Publication CyteType

Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics

Gautam Ahuja et al. demonstrate how multi-agent AI systems enable evidence-based cell annotation in scRNA-seq data.

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Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis
Publication

Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis

Sara Palo et al. reveal how chromatin accessibility patterns shape lineage plasticity during blood cell development.

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Building Cell Atlases - Navigating Biology Like Google Maps Navigates the World
Blog Tutorials

Building Cell Atlases - Navigating Biology Like Google Maps Navigates the World

Discover how building cell atlases parallels Google Maps - transforming scattered cellular data into integrated, navigable maps for drug discovery.

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Understanding Batch Effect and Normalization in scRNA-Seq Data
Blog Tutorials

Understanding Batch Effect and Normalization in scRNA-Seq Data

A practical guide to batch effect correction and normalization in scRNA-seq data, covering when integration is justified, leading tools including Harmony, Seurat, BBKNN, and scVI, evaluation strategies, and how to avoid overcorrection.

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What is Single Cell Transcriptomics?
Blog Tutorials

What is Single Cell Transcriptomics?

Discover single-cell transcriptomics, a transformative technique for analyzing gene expression at the cellular level in biology and medicine.

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Navigating the Complexity of Single-Cell RNA-Seq Data Analysis
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Navigating the Complexity of Single-Cell RNA-Seq Data Analysis

Explore key challenges and advanced strategies in scRNA-seq data analysis for both new and experienced researchers.

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Overcoming Bioinformatics Skill Gaps in Single-Cell Research
Blog Tutorials

Overcoming Bioinformatics Skill Gaps in Single-Cell Research

Discover solutions to bridge bioinformatics skill gaps in single-cell research, enabling easier scRNA-seq analysis for wet-lab scientists.

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Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Publication

Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

Rebecca Warfvinge et al. link single-cell multi-omics heterogeneity in CML to variations in therapy response.

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Tracking early mammalian organogenesis – prediction and validation of differentiation trajectories at whole organism scale
Publication

Tracking early mammalian organogenesis – prediction and validation of differentiation trajectories at whole organism scale

Ivan Imaz-Rosshandler et al. predict and validate cell differentiation trajectories during early mammalian organogenesis.

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Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia
Publication

Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia

Daniel Zucha et al. map glial cell responses over time in a mouse brain ischemia model using spatial transcriptomics.

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EpiCarousel: memory- and time-efficient identification of metacells for atlas-level single-cell chromatin accessibility data
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EpiCarousel: memory- and time-efficient identification of metacells for atlas-level single-cell chromatin accessibility data

Sijie Li et al. introduce EpiCarousel for efficient metacell identification in large-scale chromatin accessibility datasets.

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CTEC: a cross-tabulation ensemble clustering approach for single-cell RNA sequencing data analysis
Publication Tools

CTEC: a cross-tabulation ensemble clustering approach for single-cell RNA sequencing data analysis

Liang Wang et al. present CTEC, an ensemble clustering method for robust scRNA-seq data analysis.

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Characterization of regeneration initiating cells during Xenopus laevis tail regeneration
Publication

Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

Radek Sindelka et al. characterize cells that initiate regeneration during Xenopus tail regrowth.

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